2017-04-09 20:20:192017-03-31 14:40:40
description
chromosome positioning near the pole and transport through the polar septum / antagonist of SMC complex to the origin of replication
locus
BSU40960
proteinLength
282
geneLength
846
function
chromosome positioning before asymmetric septation,
product
centromer-binding protein
essential
no
ec
names
parB
spo0J
spo0JB
outlinks
bsupath
parB_4205556_4206404_-1
outlinks
uniprot
P26497
outlinks
subtilist
gene_detail BG10054
outlinks
bsu
BSU40960
genomicContext
[[this]]
categories
[[this]]
Gene
Coordinates
4,205,556 -> 4,206,404
The protein
Catalyzed reaction/ biological activity
inhibits [[protein|ParA]] dimerization and concomitant DNA-binding activity by stimulating [[protein|ParA]] ATPase activity [Pubmed|21235642]
recruits the condensin complex to the DNA origin region [Pubmed|24440393]
the dimer binds specifcally to the centromere-like ''parS'' sequence [Pubmed|25572315]
The protein
Protein family
parB family (according to Swiss-Prot)
The protein
Paralogous protein(s)
[[protein|Noc]]
The protein
Structure
[PDB|4UMK] (complex with ''parS'' DNA)
The protein
[SW|Localization]
chromosome centromer [Pubmed|23475963]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
1S135 ( ''spo0J''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S135&Search=1S135 BGSC]
1S136 ( ''spo0J''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S136&Search=1S136 BGSC]
1S137 ( ''spo0J''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S137&Search=1S137 BGSC]
Labs working on this gene/protein
[SW|Heath Murray], Centre for Bacterial Cell Biology, Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/heath.murray homepage]
References
Reviews
References
Original publications